Publications

Full pulblication list in ORCID and Google Scholar


  1. Xiulian Yu, Tao Ni, George Munson, Peijun Zhang, Robert J. C. Gilbert Structures of perforin-2 in solution and on a membrane reveal mechanisms for pore formation BioRxiv doi: https://doi.org/10.1101/2022.06.14.496043

  2. Williams SI*, Yu X*, Ni T, Gilbert RJC, Stansfeld PJ. Structural, Functional and Computational Studies of Membrane Recognition by Plasmodium Perforin-Like Proteins 1 and 2. J Mol Biol. 2022 Jul 15;434(13):167642. doi: 10.1016/j.jmb.2022.167642. Epub 2022 May 19. PMID: 35598848.

  3. Ni T*, Sun Y*, Burn W, Al-Hazeem MMJ, Zhu Y, Yu X, Liu LN, Zhang P. Structure and assembly of cargo Rubisco in two native α-carboxysomes. Nat Commun. 2022 Jul 25;13(1):4299. doi: 10.1038/s41467-022-32004-w. PMID: 35879301; PMCID: PMC9314367.

  4. Ni T*, Zhu Y*, Yang Z*, Xu C, Chaban Y, Nesterova T, Ning J, Böcking T, Parker MW, Monnie C, Ahn J, Perilla JR, Zhang P. Structure of native HIV-1 cores and their interactions with IP6 and CypA. Sci Adv. 2021 Nov 19;7(47):eabj5715. doi: 10.1126/sciadv.abj5715. Epub 2021 Nov 19. PMID: 34797722; PMCID: PMC8604400.

  5. Ni T*, Frosio T*, Mendonça L*, Sheng Y, Clare D, Himes BA, Zhang P. High-resolution in situ structure determination by cryo-electron tomography and subtomogram averaging using emClarity. Nat Protoc. 2022 Feb;17(2):421-444. doi: 10.1038/s41596-021-00648-5. Epub 2022 Jan 12. PMID: 35022621.

  6. Mendonça L, Howe A, Gilchrist JB, Sheng Y, Sun D, Knight ML, Zanetti-Domingues LC, Bateman B, Krebs AS, Chen L, Radecke J, Li VD, Ni T, Kounatidis I, Koronfel MA, Szynkiewicz M, Harkiolaki M, Martin-Fernandez ML, James W, Zhang P. Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress. Nat Commun. 2021 Jul 30;12(1):4629. doi: 0.1038/s41467-021-24887-y. PMID: 34330917; PMCID: PMC8324836.

  7. Huokko T, Ni T, Dykes GF, Simpson DM, Brownridge P, Conradi FD, Beynon RJ, Nixon PJ, Mullineaux CW, Zhang P, Liu LN. Probing the biogenesis pathway and dynamics of thylakoid membranes. Nat Commun. 2021 Jun 9;12(1):3475. doi: 10.1038/s41467-021-23680-1. PMID: 34108457; PMCID: PMC8190092.

  8. Liu C, Mendonça L, Yang Y, Gao Y, Shen C, Liu J, Ni T, Ju B, Liu C, Tang X, Wei J, Ma X, Zhu Y, Liu W, Xu S, Liu Y, Yuan J, Wu J, Liu Z, Zhang Z, Liu L, Wang P, Zhang P. The Architecture of Inactivated SARS-CoV-2 with Postfusion Spikes Revealed by Cryo-EM and Cryo-ET. Structure. 2020 Nov 3;28(11):1218-1224.e4. doi: 10.1016/j.str.2020.10.001. Epub 2020 Oct 15. PMID: 33058760; PMCID: PMC7557167.

  9. Ni T, Gerard S, Zhao G, Dent K, Ning J, Zhou J, Shi J, Anderson-Daniels J, Li W, Jang S, Engelman AN, Aiken C, Zhang P. Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat Struct Mol Biol. 2020 Sep;27(9):855-862. doi: 10.1038/s41594-020-0467-8. Epub 2020 Aug 3. PMID: 32747784; PMCID: PMC8064030.

  10. Ni T*, Jiao F*, Yu X*, Aden S, Ginger L, Williams SI, Bai F, Pražák V, Karia D, Stansfeld P, Zhang P, Munson G, Anderluh G, Scheuring S, Gilbert RJC. Structure and mechanism of bactericidal mammalian perforin-2, an ancient agent of innate immunity. Sci Adv. 2020 Jan 29;6(5):eaax8286. doi: 10.1126/sciadv.aax8286. PMID: 32064340; PMCID: PMC6989145.

  11. Hao Y, Zhou D, Ni T, Karia D, Kotecha A, Wang X, Rao Z, Jones EY, Fry EE, Ren J, Stuart DI. Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10. Nat Commun. 2020 Jan 7;11(1):38. doi:10.1038/s41467-019-13936-2. PMID: 31911601; PMCID: PMC6946704.

  12. Ni T, Williams SI, Rezelj S, Anderluh G, Harlos K, Stansfeld PJ, Gilbert RJC. Structures of monomeric and oligomeric forms of the Toxoplasma gondii perforin-like protein 1. Sci Adv. 2018 Mar 21;4(3):eaaq0762. doi: 10.1126/sciadv.aaq0762. PMID: 29750191; PMCID: PMC5943054.

  13. Ni T, Gilbert RJC. Repurposing a pore: highly conserved perforin-like proteins with alternative mechanisms. Philos Trans R Soc Lond B Biol Sci. 2017 Aug 5;372(1726):20160212. doi: 10.1098/rstb.2016.0212. PMID: 28630152; PMCID: PMC5483515.

  14. Ni T, Kalli AC, Naughton FB, Yates LA, Naneh O, Kozorog M, Anderluh G, Sansom MS, Gilbert RJ. Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain. Biochem J. 2017 Feb 15;474(4):539-556. doi: 10.1042/BCJ20160791. Epub 2016 Dec 14. PMID: 27974389; PMCID: PMC5290484.

  15. Kong Y, Janssen BJ, Malinauskas T, Vangoor VR, Coles CH, Kaufmann R, Ni T, Gilbert RJ, Padilla-Parra S, Pasterkamp RJ, Jones EY. Structural Basis for Plexin Activation and Regulation. Neuron. 2016 Aug 3;91(3):548-60. doi: 10.1016/j.neuron.2016.06.018. Epub 2016 Jul 7. PMID: 27397516; PMCID: PMC4980550.

  16. Lu J, Fang L, Zheng H, Lao J, Yang F, Sun L, Xiao J, Lin J, Song T, Ni T, Raghwani J, Ke C, Faria NR, Bowden TA, Pybus OG, Li H. The Evolution and Transmission of Epidemic GII.17 Noroviruses. J Infect Dis. 2016 Aug 15;214(4):556-64. doi: 10.1093/infdis/jiw208. Epub 2016 May 24. PMID: 27354370; PMCID: PMC4957445.

  17. Ni T, Harlos K, Gilbert R. Structure of astrotactin-2: a conserved vertebrate-specific and perforin-like membrane protein involved in neuronal development. Open Biol. 2016 May;6(5):160053. doi: 10.1098/rsob.160053. Epub 2016 May 4. PMID: 27249642; PMCID: PMC4892435.

  18. Yu ZQ, Ni T, Hong B, Wang HY, Jiang FJ, Zou S, Chen Y, Zheng XL, Klionsky DJ, Liang Y, Xie Z. Dual roles of Atg8-PE deconjugation by Atg4 in autophagy. Autophagy. 2012 Jun;8(6):883-92. doi: 10.4161/auto.19652. Epub 2012 Jun 1. PMID: 22652539; PMCID: PMC3427254.